Beta-carotene

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Synonym(s)

Betacarotene; Beta-carotene; carotene; Carotene

Definition
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Beta-carotene, also known as beta-carotene (CAS No.:7235-40-7) is a natural tetraterpene, which occurs naturally in all green parts of the plant in addition to other carotenes (alpha- and gamma-carotene), chlorophyll and lutein. In the animal organism it is found in fatty tissue and milk, among other things. Beta-carotene is also known as provitamin A (see alsovitamin A).

Indication
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Limited indication
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Renal insufficiency.

Complication(s)
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Hypervitaminosis when taking vitamin A.

Dosage and method of use
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  • Polymorphic light dermatosis, erythropoietic protoporphyria: initial 50-200 mg/day p.o., then slow dose reduction.
  • Vitiligo: 3-5 times 25 mg/day p.o. over 3-5 weeks, then reduction to 1-2 times 25 mg/day.

Interactions
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Alcohol consumption can reduce β-carotene clearance; neomycin reduces β-carotene uptake.

Contraindication
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Hypersensitivity to the active ingredient, liver damage.

Preparations
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Carotenes