Apigenin
Synonym(s)
4`,5,7-trihydroxyflavone
DefinitionThis section has been translated automatically.
Pale yellow plant dye that can be found in numerous plants, such as Achillea millifolium(yarrow), Matricaria recutita(true camomile), Chamaemelum nobile and others. Apigenin is the aglycone of apiin.
IngredientsThis section has been translated automatically.
Chemically it is a flavone derivative. Apigenin is the aglucone of apiin. Apigenin acts experimentally cytostatic or antiproliferative (detectable in melanoma cell cultures), antiviral (Hakobyan et al. 2016). A UV-protective effect could be demonstrated in keratinocyte cultures. Furthermore, it is an inhibitor of human oestrogen synthetase. Apiin is the flavone glycoside of apigenin.
LiteratureThis section has been translated automatically.
- Bridgeman BB et al (2016) Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention. Cell signal 28:460-468.
- Hakobyan A et al. (2016) Apigenin inhibits African swine fever virus infection in vitro. Arch virol 161:3445-3453.
- Hasnat MA et al. (2015) Apigenin Attenuates Melanoma Cellby Inducing Anoikis t hrough Integrin and Focal Adhesion Kinase Inhibition Molecules 20:21157-21166.
- Patil RH et al (2016) Anti-Inflammatory Effect of Apigenin on LPS-Induced Pro-Inflammatory Mediators and AP-1 Factors in Human Lung Epithelial Cells. Inflammation 39:138-147.
- Song M et al (2016) Apigenin protects mice from pneumococcal pneumonia by inhibiting the cytolytic activity of pneumolysin. Fitoterapia 115:31-36.