Synonym(s)
Horse Chestnut Extract
DefinitionThis section has been translated automatically.
Mixture of esterified triterpene saponins (see below triterpene) from the seeds of the horse chestnut.
EffectsThis section has been translated automatically.
Low spasmolytic, antiphlogistic, anti-edematous, increase of capillary permeability (slows down the flow of water into the extracapillary space).
Notice! Percutaneous absorption is questionable!
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Field of application/useThis section has been translated automatically.
Chronic venous insufficiency, post-thrombotic syndrome, leg ulcers, post-traumatic and postoperative soft tissue swelling, hemorrhoids.
DosageThis section has been translated automatically.
- Systemic: Inital 3 times 20-40 mg/day, then 2-3 times 20 mg/day p.o.
- Topical: Apply 3 times/day thinly in the affected area.
Undesirable effectsThis section has been translated automatically.
With systemic use danger of kidney dysfunction up to kidney failure, danger of thrombosis. With topical appl.: allergic skin reactions.
Standard concentrationThis section has been translated automatically.
0.76-2% in ointments, solutions and gels.
ContraindicationThis section has been translated automatically.
Topical appl. Paragroup allergy (ointment), application on mucous membranes or inflamed skin areas and open wounds.
Trade namesThis section has been translated automatically.
Reparil, Venostasin, Essaven® Gel, Venoplant® Gel
Prof. Dr. med. Peter Altmeyer
Prof. Dr. med. Martina Bacharach-Buhles