Trichinella

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 10.04.2021

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History
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Owen, 1835

Definition
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The genus Trichinella (trichinae) in the worm class of nematodes, contains as the most important human pathological species Trichinella spiralis and Trichinella britovi, both causative agents of trichinosis (trichinellosis), which, however, is now rare in Central Europe due to trichinella testing. In Eastern Europe and Greece (Dimzas D et al. 2019), smaller outbreaks have been recorded repeatedly in the past (Vutova K et al. 2020; Pavic S et al. 2020), with both species being equally detected. Apparently, deliberate "alternative" pig husbandry played a role in these outbreaks. In tropical areas, trichinella is not of great importance.

In principle, all mammals are susceptible, but natural infections are most likely in carnivores and omnivores such as the fox and the pig. In Central Europe, the red fox is considered the most important reservoir of the pathogen.

Pathogen
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Humapathologically important species are:

Clinical picture
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The clinical course depends on the number of incorporated Trichinella larvae. Already 50 larvae can cause clear clinical symptoms. With a larger number of larvae, there are considerable systemic reactions such as: like fever, intestinal colic, diarrhoea, muscle pain. Edema of the face (eyelid edema), macular exanthema, subungual splinter hemorrhages (see below Trichinosis).

Note(s)
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In Germany and Switzerland, trichinosis (trichinellosis) in humans is notifiable.

Literature
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  1. Cortes-Blanco M et al. (2002) Outbreak of trichinellosis in Caceres, Spain, December 2001-February 2002 Euro Surveill 7: 136-138.
  2. Dimzas D et al. (2019) Human trichinellosis caused by Trichinella britovi in Greece, and literature review. J Helminthol 94:e33
  3. Holstein A et al. (1999) Father and son with muscle pain and loss of muscle strength. Acute trichinosis. Internist 40: 673-677
  4. Liu M et al (2002) Trichinellosis in China: epidemiology and control. Trends Parasitol 18: 553-556
  5. Owen R (1835) Description of a microscopic entozoon infesting the muscles of the human body. London Med Gaz 16: 125-127
  6. Pavic S et al (2020) Trichinella britovi outbreak: Epidemiological, clinical, and biological features. Med Mal Infect 50:520-524.
  7. Roy SL (2003) Trichinellosis surveillance--United States, 1997-2001. MMWR Surveill Summ 52: 1-8.
  8. Virchow R (1859) Recherches sur le developpement de la trichina spiralis (ce ver devient adulte dans l'intestin du chien). CR Seanc Acad Sci 49: 660-662
  9. Vutova K et al. (2020) Clinical and epidemiological descriptions from trichinellosis outbreaks in Bulgaria. Exp Parasitol 212:107874.
  10. Zenker FA (1860) Ueber die Trichinen-krankheit des Menschen. Arch Pathol Anat Physiol Klin Med 18: 561-572.

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Last updated on: 10.04.2021