DefinitionThis section has been translated automatically.
Salp15 Iric-1 is a Salp15 homolog that has been identified in I. ricinus.
General informationThis section has been translated automatically.
The salivary protein Salp15 of I. scapularis binds with high affinity to the outer surface protein (Osp) C of B. burgdorferi and protects the spirochete from antibody-mediated killing.
Salp15 Iric-1 is a Salp15 homolog that has been identified in I. ricinus. Like Salp15, the salivary protein binds to B. burgdorferi OspC. This binding protects the spirochete from antibody-mediated killing in vitro and in vivo. Salp15 Iric-1 is able to bind to OspC of B. garinii and B. afzelii.