Mycobacterium xenopi

Last updated on: 21.02.2023

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Definition
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M. xenopi is detected in tap water and is therefore of no clinical relevance in most cases, but can cause pulmonary infections in other underlying diseases (Varadi RG et al. 2009).

Dosage and method of use
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Although a variety of drugs are tested sensitively in resistance testing of M. xenopi (RMP, clarithromycin, fluoroquinolones, PTH; variable in INH and EMB), there is no confirmed effective therapy (Varadi RG et al. 2009).

For disease caused by M. xenopi, ATS/IDSA recommend the same triple combination as for M. avium, but isoniazid is considered quite effective in vivo, similar to the ratios for M. kansasii (Griffith DE et al. 2007).

Literature
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  1. Griffith DE et al (2007) Am J Respir Crit Care Med 175: 367-416.
  2. Saliba J et al (2021) A Rare Case of Henoch-Schönlein Purpura and Mycobacterium xenopi Pulmonary Infection. Cureus 13:e13533.
  3. Varadi RG et al (2009) Pulmonary Mycobacterium xenopi infection in non-HIV-infected patients: a systematic review. Int J Tuberc Lung Dis 13: 1210-1218.

Incoming links (1)

Nontuberculous Mycobacteria;

Last updated on: 21.02.2023