Viruses "abuse" cellular transport and receptor proteins to gain entry into the cell. The high specificity of this recognition is due to close co-evolution of viral receptor domains and structural elements of cellular surface proteins. The effect of viral replication on the host cell itself is termed the cytopathic effect (CPE), and the effects on the entire host organism are termed viral disease. In any case, viruses possess the armamentarium to influence the complete synthesis apparatus of a cell (nucleic acid + protein synthesis) in such a way that predominantly viral products are produced.
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Cytopathogenic effect of virus
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Literature
- Adams MJ et al (2017) 50 years of the International Committee on Taxonomy of Viruses: progress and prospects. Arch Virol 162:1441-1446.
- Hof H (2019). General virology. In: Hof H, Schlüter D, Dörries R, eds Dual series medical microbiology. 7th, completely revised and expanded edition. Stuttgart: Thieme p 168-180
- Simmonds P et al.(2018) Virus classification - where do you draw the line? Arch Virol 163:2037-2046.