X-linked recessive inheritance

Last updated on: 27.07.2021

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Definition
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Inheritance in which the causative gene is located on the X chromosome and leads to the expression of the trait in males (hemizygous). Females are only trait carriers if they have inherited the causative allele twice (homozygous). Heterozygous (single allele) affected women usually do not show clinical symptoms, but are carriers of the trait and have a 50 percent risk of affected sons and daughters, who in turn are carriers.

Last updated on: 27.07.2021

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