DefinitionThis section has been translated automatically.
The TSLP gene (TSLP stands for: Thymic Stromal Lymphopoietin) is a protein coding gene located on chromosome 5q22.1. Alternative splicing of this gene results in several transcript variants.
Note(s)This section has been translated automatically.
In 2021, a monoclonal antibody against TSLP was approved for the treatment of severe asthma.
LiteratureThis section has been translated automatically.
- Ebina-Shibuya R et al (2023) Role of thymic stromal lymphopoietin in allergy and beyond. Nat Rev Immunol 23: 24-37.
- Gauvreau GM et al (2020) Expert Opin Ther Targets PMID: 32567399 Review.
- Roan F et al (2019) Epithelial cell-derived cytokines: more than an alarm signal. J Clin Invest 129:1441-1451.
- Wang SH et al (2021) Thymic stromal lymphopoietin in cutaneous immune-mediated diseases. Front Immunol 12:698522.
- Ziegler SF et al (2013) The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol 66:129-155.
- Zhou G et al (2023) Clinical trials of antibody drugs in the treatments of atopic dermatitis. Front Med (Lausanne) 10:1229539.
