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spontaneous mutation

Last updated on: 02.07.2024

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Definition
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Term used in genetics. A spontaneous mutation is a random mutation for which no external causes are known. An example is the chemical decay of a nucleotide - cytosine spontaneously deaminates oxidatively to uracil. As the majority of DNA does not code for gEne, most spontaneous mutations go unnoticed. However, if spontaneous mutations occur in a gene, its function can be impaired or completely altered.

The opposite of a spontaneous mutation is an "induced mutation".

Last updated on: 02.07.2024

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