SPINK11-gene

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 10.05.2021

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Definition
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SPINK11, along with SPINK8, SPINK10, and SPINK12, is highly expressed in the mouse epididymis. Apparently, the protease SPINK11 contributes to the regulation of sperm maturation by regulating proteolytic processing of the sperm membrane during epididymal transit.

Literature
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  1. Jalkanen J et al.(2006) Novel epididymal protease inhibitors with Kazal or WAP family domain. Biochem Biophys Res Commun 349:245-254.

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Last updated on: 10.05.2021