SIRS is the acronym for "Systemic Inflammatory Response Syndrome". The score defines a misdirected inflammatory reaction of the organism and includes the following symptoms:
- Fever (≥38°C) or hypothermia (≤36°C) confirmed by rectal or intravascular or vesical measurement, tachycardia (heart rate ≥90 /min),
- Tachypnea (frequency ≥20/min) or hyperventilation (PaCO2 ≤4.3 kPa/ ≤33 mmHg),
- Leukocytosis (≤4000/mm3) or leukopenia (≤4000/mm3) or ≥10% immature neutrophil granulocytes in the differential blood count