rNTP

Last updated on: 08.09.2024

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DefinitionThis section has been translated automatically.

rNTP is the acronym for ribonucleoside triphosphate. These are the building blocks used to synthesize RNA during transcription . rNTPs are essential molecules consisting of a ribonucleoside and three phosphate groups. They play a central role in RNA synthesis as they provide the nucleotides that are incorporated into the growing RNA chain.

PathophysiologyThis section has been translated automatically.

Function of rNTPs in RNA synthesis:

  • Energy source: The hydrolysis of rNTPs provides the necessary energy for the synthesis of RNA. At each step of RNA synthesis, an rNTP is incorporated and energy is released to form the chemical bonds.
  • Nucleotide building blocks: rNTPs are the direct precursors of RNA molecules. During transcription, they are complementarily incorporated according to the DNA sequence of the gene (A with U, T with A, C with Three phosphate groups: These phosphate groups are crucial for energy transfer during RNA synthesis. During polymerization, the energy released during the hydrolysis of the phosphate bonds (especially the bond between the second and third phosphate) is used to form the phosphodiester bond between the nucleotides.

Last updated on: 08.09.2024