Prp

Penicillin-resistant pneumococci play only a minor role in antibiotic therapy. Occasionally occurring intermediate pencillin-sensitive pneumococci can be treated well with higher doses of pencillin or with a 3rd gene cephalosporin(ceftriaxone or cefotaxime). In rare pneumococcal infections with pronounced penicillin resistance (especially in the presence of meningitis), ceftriaxone should be combined with vancomycin. Alternatively, ceftarolin may be considered.

1. Huggett S et al (2018) Antibiotics Primer 2018/2019 Asclepius, Medical Scientific Publishing Company. S.51-52