Parathyroid hormone

Single-chain peptide hormone consisting of 84 amino acids. The synthesis takes place via higher molecular precursors (preproPTH →proPTH→intaktes PTH ) in the epithelial corpuscles. The secretion of the hormone is primarily regulated by the concentration of ionized calcium . Hypercalcemia and 1,25(OH)2-Vit.D3 inhibit PTH secretion. The half-life of PTH in blood is about 2 min.

Standard value: The reference range is between 15 - 65 ng/l

Pathologically decreased: hypoparathyroidism, non-parathyroid hypercalcemia

Pathologically increased: primary and secondary hyperparathyroidism, pseudohyperparathyroidism, malabsorption syndrome