Milan criteria

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

Milan Criteria

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DefinitionThis section has been translated automatically.

The Milan Criteria or Milan Criteria apply to patients with hepatocellular carcinoma (HCC) in conjunction with liver cirrhosis. The criteria are used to assess the chances of success of liver transplantation and are used for the listing for liver transplantation. According to scientific studies, patients who are transplanted within the Milan criteria should have a better long-term survival (75% after 4 years).

The Milan Criteria are defined as follows:

  • 1 lesion < 5 cm
  • up to 3 lesions < 3 cm
  • no extrahepatic manifestation
  • no vascular invasion (e.g. tumor thrombosis of the portal vein or liver veins)

Note(s)This section has been translated automatically.

Before a liver transplantation (LTX), local ablative procedures (e.g. TACE) are often used (bridging to LTX, or downstaging to meet the Milan criteria)

LiteratureThis section has been translated automatically.

  1. Mazzaferro V et al (1996) Liver transplantation for the treatment of small hepatocellular carcinomas inpatients with cirrhosis.N Engl J Med 334:693-699.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer