Megaloblastic anemia D53.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Deficiency of vitamin B12 (= cobalamin) and/or folic acid with DNA synthesis disorder and nuclear maturation disorder of myelopoesis and occurrence of megaloblasts.
Main symptom: Megaloblastic anemia; in case of vitamin B12 deficiency additional neurological and gastrointestinal symptoms.

Occurrence/Epidemiology
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The most common are megaloblastic anaemias due to vitamin B12 deficiency. Incidence: 9 cases/100.000 inhabitants/year. Increase in old age

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Last updated on: 29.10.2020