Malassezia-sepsisP36.-; P37.7
Synonym(s)
DefinitionThis section has been translated automatically.
Rare, severe catheter-induced systemic infection with Malassezia species (M. pachydermatis, M. furfur), affecting mainly immunocompromised adults or newborns pre-damaged by various diseases. In a larger Southeast Asian study on isolates in sepsis patients (n=2155), Candida species were detected in 91.9% of cases (Lin SY et al. 2019). In the non-yeast isolates (8.1%) 175 non-Candida yeasts could be detected (Lin SY et al. 2019). Of these isolates, 146 could be assigned to the ENSY group (Echinocandin non-susceptible yeast) such as Cryptococcus (109 isolates), Trichosporon (23 isolates), Rhodotorula (10 isolates) and Malassezia (4 isolates).
EtiopathogenesisThis section has been translated automatically.
Nosocomial infection in parenteral nutrition
TherapyThis section has been translated automatically.
Azole antifungals: Fluconazole (FLZ), Itraconazole, (ITZ), Posaconazole (POS), Voriconazole (VOR). Antibiograms are useful because in individual cases resistance to azoles is detected (Cafarchia C et al. 2015).
LiteratureThis section has been translated automatically.
- Cafarchia C et al (2015) Azole susceptibility of Malassezia pachydermatis and Malassezia furfur and tentative epidemiological cut-off values. Med Mycol 53:743-748.
- Sizun J et al (1994) Malassezia furfur-related colonization and infection of central venous catheters. A prospective study in a pediatric intensive care unit. Intensive Care Medicine 20: 496-499
- John G (1985) Catheter-Related Infection in Infants Due to an Unusual Lipophilic Yeast-Malassezia furfur. Pediatrics76: 896-900
- Lin SY et al (2019) The epidemiology of non-Candida yeast isolated from blood: The Asia Surveillance Study. Mycoses 62:112-120.