Major-Infektionen

In primary immunodeficiencies, the term "major infections" is used to distinguish pneumonia, meningitis, sepsis, osteomyelitis and invasive abscesses from so-called "minor infections", such as otitis media, sinusitis, bronchitis and superficial skin abscesses. Even if the occurrence of major infections predominates in primary immunodeficiencies, persistent or recurrent minor infections can also be an expression of a primary immunodeficiency.

1. Aghamohammadi A et al. (2008) Immunologic evaluation of patients with recurrent ear, nose, and throat infections. Am J Otolaryngol 29:385- 392.
2. Owayed A et al (2016) Sinopulmonary Complications in Subjects With Primary Immunodeficiency. Respir Care 61:1067-1072.