Ldh

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

Lactate dehydrogenase

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DefinitionThis section has been translated automatically.

LDH, also called lactate dehydrogenase, is an ubiquitously occurring enzyme that catalyses the oxidation of lactate to pyruvate. LDH is formed from the genetically determined subunits H (heart type) and M (Myuekl type). 5 cytoplasmically occurring isoenzymes, LDH1-LDH5.

The ubiquitous enzyme shows the highest activity in skeletal muscles, heart muscle, kidney, brain and liver. Due to the lack of organ specificity, the enzyme is a less suitable diagnostic parameter.

General informationThis section has been translated automatically.

Standard value:

  • Adults: < 250 U/l
  • Children (1-15 years): < 400 U/l
  • Children < 1 year: <450 U/l

Pathologically increased: myocardial infarction, shock, pulmonary embolism, hemolysis, malignancies, myopathies, hepatic parenchyma damage, cardiac muscle damage, mononucleosis, hemolytic or megaloblastic anemia, thrombotic-thrombocytopenic purpura, acute or chronic myeloid leukemia.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer