Synonym(s)
8-Methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]oct-3-yl]-3-hydroxy-2-phenyl-propanoatium bromide; CAS number: 22254-24-6 (Ipratropiumbromid); CAS number: 60205-81-4; CAS number: 66985-17-9; Muscarinic receptor antagonist; N-(2-propyl)atropinium bromide; Parasympatholytic
DefinitionThis section has been translated automatically.
Anticholinergic, bronchodilator.
Half-lifeThis section has been translated automatically.
3,2 h
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Pharmacodynamics (Effect)This section has been translated automatically.
Competitive antagonism of acetylcholine at the muscarinic receptor.
IndicationThis section has been translated automatically.
Bronchial asthma, chronic obstructive bronchitis (COPD). Note:In the therapy of bronchial asthma the substance, like other muscarinic receptor antagonists, is hardly used any more.
Limited indicationThis section has been translated automatically.
Pregnancy, nursing, tachyarrhythmia.
Dosage and method of useThis section has been translated automatically.
3-4 times/day 1-2 strokes per inhalation, max. 12 strokes/day.
Undesirable effectsThis section has been translated automatically.
Allergic reactions, accommodation disorders, micturition disorders, dry mouth, glaucoma, bronchospasm.
InteractionsThis section has been translated automatically.
Enhancement of the effect of β sympathomimetics and theophylline, enhanced anticholinergic effect in anticholinergic drugs, neuroleptics and tricyclic antidepressants
ContraindicationThis section has been translated automatically.
Hypersensitivity to the active substance or atropine and its derivatives, narrow-angle glaucoma, prostate hypertrophy.
PreparationsThis section has been translated automatically.
Atrovent©, Berodual©
Prof. Dr. med. Peter Altmeyer
Prof. Dr. med. Martina Bacharach-Buhles
