IL7R Gene

Last updated on: 11.03.2022

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DefinitionThis section has been translated automatically.

The IL7R gene (IL7R stands for Interleukin 7 Receptor) is a protein coding gene located on chromosome 5p13.2. The protein encoded by this gene is a receptor for interleukin-7 (IL-7).

The function of this receptor requires the gamma chain of the interleukin-2 receptor (IL2RG), a common gamma chain of the receptors of several cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development.

LiteratureThis section has been translated automatically.

Silva A et al (2021) Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma. Blood138:1040-1052.

Last updated on: 11.03.2022