IL10RA Gene

The IL10RA gene (IL10RA stands for Interleukin 10 Receptor Subunit Alpha) is a protein coding gene located on chromosome 11q23.3. The protein encoded by this gene is a receptor unit (alpha subunit of the IL10 receptor complex) for interleukin 10. Two transcript variants have been found for this gene, one protein-coding and the other non-protein-coding.

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4. Mao H et al (2012) Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatal-onset Crohn's disease. Genes Immun 13: 437-442.