DefinitionThis section has been translated automatically.
The GPR55 gene, also known as the G protein-coupled receptor55 gene, is located on chromosome 2q37.1 and encodes a protein belonging to the G protein-coupled receptor superfamily.
General informationThis section has been translated automatically.
The encoded integral membrane protein is probably a cannabinoid receptor . It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. The GPR55 gene may play a role in bone physiology by regulating osteoclast number and function.
Diseases associated with GPR55 include cannabis abuse and lysine-uric protein intolerance. An important paralog of this gene is GPR35.
LiteratureThis section has been translated automatically.
- Cho YJ et al (2020) Ginseng Gintonin Contains Ligands for GPR40 and GPR55. Molecules 25:1102
- Celorrio M et al (2017) GPR55: A therapeutic target for Parkinson's disease? Neuropharmacology 125:319-332.
