Endpoint

The endpoint (the objective criterion) is the measurand defined in the protocol that has the strongest power to answer the key question of a clinical trial. It should be a criterion validated according to scientific standards, by which, for example, the efficacy or tolerability of the drug or medical device is investigated.

Each study has a "primary endpoint". This contains the measurement parameter of the main research question of the study. This main question essentially determines the size and significance of the study and thus the correct interpretation of the study results. Most studies have only one main research question.