DefinitionThis section has been translated automatically.
The DUSP22 gene (DUSP22 stands for "Dual Specificity Phosphatase 22") is a protein coding gene located on chromosome 6p25.3.
General informationThis section has been translated automatically.
Phosphatase encoded by the DUSP22 gene facilitates non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity. It is involved in several processes, including cellular response to epidermal growth factor stimulus, negative regulation of focal adhesion formation, and negative regulation of non-membrane spanning protein tyrosine kinase activity. DUSP22 acts upstream in the negative regulation of transcription by RNA polymerase II.
Diseases associated with DUSP22 include:
Breast implant-associated anaplastic large cell lymphoma. This is a peripheral T-cell lymphoma that develops around breast implants with a structured surface and is confined to the capsule.
