Creatine kinase
Synonym(s)
DefinitionThis section has been translated automatically.
Creatine kinases are dimeric enzymes that occur in the cytosol of various energy-consuming cells. The determination of creatine kinase is particularly important in skeletal muscle diseases. CK-MB is most active in the myocardium. Although not fully cardiospecific, it is still used as a biochemical parameter for acute myocardial infarction in conjunction with total CK after cardiac troponins .
General informationThis section has been translated automatically.
Standard value (total CK):
- Women < 145 U/l
- Men < 170 U/l
- Children (<6 months): <300U/l
- Infants (<6d): <700U/l
standard value (creatine kinase isoenzyme MB):
- Adults: <24U/l
Pathologically increased: Myocarditis, myocardial infarction, muscular lesions, progressive muscular dystrophy, polymyositis; rhabdomyolysis, myasthenia gravis, malignant hyperthermia, secondary myopathies, acute myocardial infarction, diagnostic and therapeutic interventions on the heart, pulmonary embolism, malignant tumours, neurological diseases with damage to the blood-brain barrier, diseases of the gastrointestinal tract, haemolysis and myeloproliferative syndrome.
Isoenzymes: CK-MM, CK-MB, CK-BB.