Cholangitis primary sclerosingK83.0

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

PSC

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DefinitionThis section has been translated automatically.

Sclerosing chronic inflammation of the extra- and intrahepatic bile ducts with consecutive destruction of the bile ducts.

Occurrence/EpidemiologyThis section has been translated automatically.

Prevalence 1:100,000 per year

EtiopathogenesisThis section has been translated automatically.

Unresolved

ManifestationThis section has been translated automatically.

Increased occurrence between the 30-50 LJ;

Clinical featuresThis section has been translated automatically.

In the early stages asymptomatic. Later unclear upper stage symptoms, weight loss, icterus, itching.

The disease is more often than not accompanied by "chronic inflammatory bowel disease" (CED), usually ulcerative colitis. Furthermore, an association with the Sjögren's syndrome is found.

LaboratoryThis section has been translated automatically.

Increased cholestasis parameters; frequent (60%) detection of ANA and ANCA (p-ANCA).

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer