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Schematic representation of EGF receptor activation by EGF and activation of the intracellular signalling cascade.

Cetuximab: Blockade of the EGF receptor by cetuximab

Cetuximab: extensive healing of psoriasis after 1-week therapy with cetuximab. figure taken from: Okamoto K et al. (2015) Cetuximab and panitumumab in a patient with colon cancer and concomitant chronic skin disease: a potential beneficial effect on psoriasis vulgaris. world JGastroenterol 21:3746-3749.