Cea

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

carcinoembyronal antigen

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DefinitionThis section has been translated automatically.

Immunohistological marker for eccrine and apocrine sweat glands.

General informationThis section has been translated automatically.

Standard value: In serum up to 5 ug/l

Pathologically elevated: in case of cazinomas in stomach, mamma, pancreas, uterus, bronchia, kidneys and thyroid glands. An unspecific slight increase is present in smokers, alcoholism, cirrhosis of the liver, emphysema, pneumonia, pancreatitis and chronic inflammatory bowel disease.

Note(s)This section has been translated automatically.

CEA is expressed in microcystic adnexal carcinomas, metastatic oat-cell carcinomas of the lung and adenocarcinomas. It is also expressed in the sebaceous glands and nevomelanocytes. CEA is mostly negative in Merkel cells, but can occasionally be positive in Merkel cell carcinomas.

LiteratureThis section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 29.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer