Images (1)

Biperides

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Synonym(s)

CAS number: 514-65-8

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Biperiden is like atropine and scopolamine a muscarinic receptor antagonist with a tertiary nitrogen. Biperiden is a synthetically produced, predominantly centrally acting pharmaceutical with the molecular formula C21H29NO. Its peripheral effects are small compared to atropine. Biperiden binds competitively to peripheral and central muscarinic receptors (especially M1-receptors). In animal experiments Biperiden influences parkinson-like conditions (tremor, rigor) caused by centrally acting cholinergic drugs.

IndicationThis section has been translated automatically.

Biperiden is used among other things as an antiparkinsonian agent. Furthermore, the substance is used for extrapyramidal side effects such as body stiffness, gaze rigidity and akathisia, which can cause many antipsychotics above a certain dose.

Note(s)This section has been translated automatically.

The first manufacturer of the substance was Wilfried Klavehn, German chemist, 1953

LiteratureThis section has been translated automatically.

  1. Graefe KH et al muscarinic receptor antagonists. In: Graefe KH et al (Eds) Pharmacology and Toxicology. Georg Thieme Publisher Stuttgart S.114-115

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer