Synonym(s)
Antibodies against smooth musculature; Anti-SMA antibodies; ASMA
DefinitionThis section has been translated automatically.
Anti-SMA antibodies are a heterogeneous group of autoantibodies directed against microfilaments, microtubules and intermediate filaments of human smooth muscle. SMA is the acronym for "smooth muscle antigen". Mainly polymerized actin is recognized as antigen. Intermediate smooth muscle filaments are found in smooth muscle cells, but also in other tissues such as liver and kidney tissue.
ImplementationThis section has been translated automatically.
Test material: Serum
Determination method: Immunofluorescence on rat kidney tissue, fibroblast cultures
Note(s)This section has been translated automatically.
Elevated levels of ASMA: autoimmune hepatitis, chronic active hepatitis; polymyositis (30% SMA detectable); concomitant phenomenon in various diseases. viral infections, post-myocardial infarction syndrome (Dressler syndrome), post-cardiotomy syndrome.
Prof. Dr. med. Peter Altmeyer