Synonym(s)
Antibodies against PLA2 receptor; Anti-GBM; PLA2-RAK
DefinitionThis section has been translated automatically.
Antibodies raised against glomerular basement membrane are found in the serum of about 75% of patients with idiopathic membranous glomerulonephritis (MGN), THS-D7A-AK at 2.5-5.0%.
Both AK are expressed on the podocyte membrane. PLA2R-R-AK show a high sensitivity (78%) and specificity (99%) with respect to MGN
General informationThis section has been translated automatically.
- DD of nephrotic syndrome: Idiopathic membranous glomerulonephritis (MGN)
- Follow-up to assess the disease activity
- Follow-up to assess a possible recurrence after kidney transplantation
- Test material: Serum
- Reference range:negative
LiteratureThis section has been translated automatically.
- Manfras B (2018) Immunodiagnostics. In: Neumeister B et al (Eds) Clinical guide to laboratory diagnostics. Elsevier GmbH S. 426
Prof. Dr. med. Peter Altmeyer