Parapsoriasis en plaques,grandes plaquesForm (Parapsoriasisen grandes plaques): completely symptom-free, yellow-brown (purpura pigmentosa-like), sharply defined spots; only when the skin is wrinkled is a cigarette-paper-like pseudoatrophic architecture of the skin surface discernible (important diagnostic sign!).
Acrocyanosis; diffuse reddish-livid skin discoloration of both mammae only occurring in cold weather with large-meshed marbling; reduced skin temperature; possible doughy, cushion-like swellings, symmetrical infestation, numbness and iris diaphragm phenomenon.
Toxic epidermal necrolysis. detailed view of a solitary, acutely occurring, perimamillary, sharply defined, slightly weeping, extensive, erosive detachment of the skin. the sample biopsies showed a vacuum-associated interfacial dermatitis with epidermal keratinocyte necroses.
Acanthosis nigricans maligna: Severe infestation of the back with hyperkeratotic papules on yellow-brown hyperpigmentation in a 75-year-old female patient with ovarian cancer.
Lymphomatoid papulosis. reflected light microscopy (detail): In the initial phase of a papule eruption a concentric or radial pattern of punctiform or garland-like vascular ectasia is visible. partially brownish background pigment (oxidative haemoglobin degradation).
Atopic eczema in children/adolescents: 3-year-old toddler with previously known atopic eczema; for several weeks increasing severe eczematization with excruciating itching, elevated nummular (also borderline) crusty and weeping plaques; evidence of gram-positive coccus.
Granuloma anulare disseminatum. general view: Non-painful, non-itching, disseminated, large plaques on the abdomen of a 43-year-old female patient. no diabetes mellitus.
Psoriasis vulgaris Psoriatic plaques around a larger and smaller (between the senile angioma shown above and the melanocytic nevus shown on the right) seborrhoeic keratoses (see also nevus, melanocytic, Meyerson's nevus).
Vitiligo: Multiple predominantly roundish vitiligo foci. A foci with a central residue of a melanocytic nevus (halo or sutton nevus) is encircled. Note: In the 14-year-old boy it is conspicuous that not a single melanocytic nevus is detectable.
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