Drug reaction, fixed: unusual image of a 3.5 x 2.5 cm measuring, crusty covered, flat ulcer on the lower leg of a 38-year-old patient as a result of repeated use of non-steroidal anti-inflammatory drugs; the reddish discolored periulcerous area and the blue-violet discoloration of the necroses result from the topical application of methylrosanilinium chloride during external therapy.
Acropathia ulcero-mutilans familiaris. large, completely areactive ulcer (at pressure point) extending to the heel bone. the 40-year-old patient has been suffering from peripheral polyneuropathy for more than 10 years with sensory disturbances for pain, temperature and touch. babinski sign is positive!
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