Contact dermatitis, toxic: Hyperkeratosis on inflammatory changed skin on the right wrist dorsally and on the back of the right hand of a 46-year-old patient.
Acrolentiginous malignant melanoma: A brown, slowly increasing spot that has existed for years. It is said that this broad-based, ulcerated, repeatedly bleeding node has been formed for a few months. Arrows mark the non-node acrolentiginous part of the tumor. A weak pigmentation zone is encircled, which histologically also turned out to be melanoma infiltration.
Graft-versus-Host-Disease. 12 months after transplantation, reaction due to transmission of allogenic immunocompetent T-lymphocytes. extensive dermatosclerosis with numerous, bizarre, skin-coloured papules and plaques.
Leishmaniasis, cutaneous. reddish-brown, 6 x 5 cm large, only slightly painful, succulent nodule that has existed for several months. previous therapy: antimycotic external agents. 1 year ago study visit to Morocco.
Melanoma malignes acrolentiginous: Brown "spot" on the left small toe that has existed for many years; for several months now it has been growing in thickness, weeping and bleeding.
Atrophodermia idiopathica et progressiva. detail section: Chronic stationary, map-like spread, brownish spots in an 18-year-old woman. The existing skin changes developed within 2 years and originally had a rather reddish-livid colour.
café-au-lait stains. reflected light microscopy: detailed view from a lesion on the thigh in a 36-year-old woman. light brown, double contoured reticulation pattern as well as intact skin field lines. no other structural features.
Nipple, accessory: solitary, 0.8 cm high, symptomless, brown plaque with a decentralized pointed conical papule and coarsely felted surface; previously known circumscribed scleroderma.
Eczema atopic: severe, generalized, severely itchy atopic eczema existing since earliest childhood with disseminated, eroded and ulcerated (scratched) reddish papules and plaques; the "dryness of the integument" with keratosis pilaris-like accentuation of the follicles is clearly visible.
Drug reaction, fixed: recurrent course with acute itchy redness 1 day after taking ibuprofen (600 mg) due to rheumatoid complaints. After 2-3 days the acute symptoms subsided with the residual hyperpigmentation shown here. The acute changes occurred strictly localized.
Melanonychia striata longitudinalis. incident light microscopy: Melanonychia striata through melanocytic nevus on the index finger in a 19-year-old woman. fine-grained longitudinal brown pigmentation below the nail plate. normal nail fold capillaries. distinct pigmentation of the cuticles.
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