X-ray keratoses L85.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Manifestation
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Occurs from 20 years after therapeutic X-ray radiation.

Clinical features
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Horny, hard excrescences on a radiodermatitis chronica.

Therapy
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In case of unfavourable localisation and multiple foci, try therapy with 5-fluorouracil (e.g. Efudix) over several weeks. If necessary, combination with acitretin (neotigason) 20 mg/day p.o. over 6-8 weeks. Start therapy 2 weeks before using 5-Fluorouracil.

Operative therapie
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Complete surgical removal with small (0.2-0.5 mm) safety distance, in case of multiple foci also electrodesiccation with combined curettage, cryosurgery or laser therapy( CO2 laser, Erbium-YAG laser).

Progression/forecast
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Without therapy, the transition to X-ray carcinoma is likely.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020