DefinitionThis section has been translated automatically.
Disease pattern in acute or chronic overdose of vitamin A. Normal vitamin A daily requirement: 5.000 IU/day.
Clinical featuresThis section has been translated automatically.
- Acute: Nausea, headache, followed by skin flaking.
- Chronic: weight loss, anorexia, lethargy, dry, irritable skin (xerosis), mucosal rashes, diffuse telogenic effluvium.
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LaboratoryThis section has been translated automatically.
Transaminases and alkaline phosphatase are elevated.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Stopping the vitamin A supply, including external or internal therapy with vitamin A acid preparations
External therapyThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Hamann K et al (1982) Chronic hypervitaminosis A with skin lesions. Dermatologist 33: 559-561
- Lips P (2003) Hypervitaminosis A and fractures. N Engl J Med 348: 347-349
- Muggia FM (1992) Vitamin A Intoxication during taxol therapy for refractory ovarian cancer J Natl Cancer Inst 18: 1444-1445
- Perrotta S et al (2003) Vitamin A and infancy. Biochemical, functional, and clinical aspects. Vitamin Horm 66: 457-591
Incoming links (6)
Cod liver oil; Hyperpigmentation, circumscribed; Hypervitaminosis; Urea cream hydrophilic 5 or 10% (nrf 11.71.); Urea emulsion, hydrophilic 5 or 10% (nrf 11.72.); Vitamins skin changes;Outgoing links (8)
Anorexia nervosa, skin changes; Contact dermatitis (overview); Pellagra; Seborrheic dermatitis of adults; Urea cream hydrophilic 5 or 10% (nrf 11.71.); Urea emulsion, hydrophilic 5 or 10% (nrf 11.72.); Urea (overview); Vitamins skin changes;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.