Synonym(s)
UVA-1 light therapy; UVA-1 radiation therapy
DefinitionThis section has been translated automatically.
Selective UV radiation therapy (light therapy) with UVA-1 rays, which cover a UV spectrum between 340-400 nm. In addition to the preferred spectrum, UVA-1 devices emit visible light as well as infrared rays and, to varying degrees, heat rays.
General definitionThis section has been translated automatically.
In the past, some therapy-related terms have become established in dermatology such as:
- High-dose UVA-1 therapy: single dose 100 - 130J/cm²
- UVA-1 cold light therapy: The radiation sources emit only a small (hardly measurable) amount of heat radiation through various filter techniques.
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EffectsThis section has been translated automatically.
UVA-1 radiation has an immunomodulatory effect and leads to apoptosis of lymphocytic inflammatory cells (especially T-helper cells). This anti-inflammatory effect is considered to be an important principle of UVA-1 therapy.
IndicationThis section has been translated automatically.
Severe atopic eczema, systemic scleroderma and circumscribed scleroderma, urticaria pigmentosa, acne vulgaris, vitiligo.
ContraindicationThis section has been translated automatically.
UVA-1 sensitive atopic eczema, polymorphic light dermatosis and other light diseases, intake of light sensitizing drugs.
Complication(s)This section has been translated automatically.
- Acute side effects: Activation of bacterial or viral infections, hyperpigmentation, dermatitis solaris in overdose.
- Long-term side effects: premature skin ageing (see also light ageing) and wrinkle formation and, to a lesser extent in relation to UVB, an increased risk of skin cancer (see also photocarcinogenesis; see also malignant melanoma).
Prof. Dr. med. Peter Altmeyer