DefinitionThis section has been translated automatically.
Epicutaneous test procedure for clarifying an unclear or questionable test reaction to better assess clinical relevance. Modification of a " repeated open application test".
IndicationThis section has been translated automatically.
Assessment of the clinical relevance of sensitization to cosmetic ingredients using finished products.
ImplementationThis section has been translated automatically.
- Application of the finished product 2 times/day for 1 week at a defined body area.
- The chosen localisation should correspond to the normal application.
- If possible, carry out a negative control: ideally a comparable product without the suspected allergen.
- The test reaction is then evaluated according to the conditions of the standard epicutaneous test.
- Indication of clinical relevance in the allergy certificate (see COADEX index below).
LiteratureThis section has been translated automatically.
- Villarama CD et al (2004) Correlations of patch test reactivity and the repeated open application test(ROAT)/provocative use test (PUT). Food Chem Toxicol 42: 1719-1725
Prof. Dr. med. Peter Altmeyer