Tuberculin skin test

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Intracutaneous test according to Mendel-Mantoux; THT

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DefinitionThis section has been translated automatically.

Type IV reaction (delayed reaction) mediated by T cells. Only limited use in BCG vaccination.

ImplementationThis section has been translated automatically.

The WHO recommended Danish reference tuberculin PPD RT 23 (Pharmore GmbH) is used. The tuberculin injection is made on the flexor side of the forearm. 2 tuberculin units are injected in 0.1ml s.c.

  • Reading after 48 and 72 h.
  • positive: induration (palpable papule) > 0,5 cm

Note(s)This section has been translated automatically.

Positive test occurs on average 8 weeks after infection with TB. A positive test indicates infection. False positive reactions are to be expected in GCG vaccinated patients. Also by cross reactions after infections by environmental mycobacteria.

A negative test makes infection by mycobacteria unlikely.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer