Tromethamine (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; CAS number: 77-86-1; Tris; Trometamol; Tromethamine

Definition
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Tromethamine is a primary amine with 3 alcoholic hydroxy groups. Tromethamine has the molecular formula: C4H11NO3.

Field of application/use
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Pharmacy: Trometamol is used in various pharmaceutical dosage forms (injection and infusion solutions, eye drops, various external agents as a stabilizing agent. It has an alkalizing effect and acts as a buffer substance.

Cosmetics: Tromethamine is used in cosmetic formulations. The amine acts as a buffer substance. Furthermore, tromethamine has a masking effect (reduces or inhibits an undesirable inherent odour or taste of the product).

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Last updated on: 29.10.2020