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Trichostrongyliasis B81.2

Author: Prof. Dr. med. Peter Altmeyer

Last updated on: 29.10.2020

Definition
This section has been translated automatically.

Nematode infection (threadworm disease).

Trichostrongylus colubrifomris and Trichostrongylus orientalis (nematodes).
The 4-8 mm long adult worms parasitize in the small intestine, the eggs are excreted with the faeces. After embryonic development in the open air, a larva hatches after 1-2 days, which matures into an infectious larva within 2-4 days. This is absorbed orally and develops into an adult worm in the intestinal tract without any tissue passage. The preparation lasts about 25 days.
Infection through salads and vegetables by contamination with larval faeces from infected animals. Occasionally, larval penetration through the skin is possible.
Circulation between ruminants and other herbivores. The pathogens are absorbed during grazing.

Dermatology

Benign, circumscribed, often painful or itchy, (inflammatory) connective tissue proliferations affecting a ...

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Mostly mild and asymptomatic course.
In case of high parasite density epigastric pain, nausea, alternating diarrhoea, anaemia, inflammation of the bile ducts.
Skin involvement is usually absent. In case of larvae penetrating the skin Larva migrans and possibly superinfection of the entry site, especially in tropical climate. Occasionally torturous non-specific perianal pruritus.

Microscopy in the chair.
Egg excretion is often low. Enrichment procedures are helpful. 75-90 x 40 µm, thick egg shell. Further embryonic development takes place in the stool (at least 16 cell morula stage).

Albendazole: 400 mg as single dose p.o.
Alternatively: Mebendazole: 2 times/day 100 mg p.o. for 3 days.
Alternative: Levamisol and Pyantel.
Alternative: Thiabendazol 25 mg/kg bw (max. 3 g total dose), divided into 2 doses for 2 days.