Trichophyton rubrum abscesses, subcutaneous B35.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Deep pustular Trichphyton rubrum infection; Subcutaneous trichophyton rubrum abscesses; Trichophyton rubrum granulomas; Trichophyton rubrum infection deep pustular; Trichophyton rubrum with mycetic formation

Definition
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Abscess formation by Trichophyton rubrum in immunocompromised patients with superficial tinea.

Clinical features
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Non-inflammatory, subcutaneous, melting nodules.

Histology
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Abscess in the lower corium, granulomatous wall structure, branched mycelium.

Diagnosis
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Negative trichophytin reaction. Pathogen culture from abscesses ( mycoses).

External therapy
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Abscess splitting and open wound treatment with disinfectant external agents e.g. polyvidon iodine ointment(e.g. Betaisodona).

Internal therapy
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griseofulvin p.o. (e.g. Likuden) Dosage: Adults 500-1000 mg/day, children 6-7 mg/kg bw/day to high-fat meal over 2 weeks. Alternatively systemic therapy with itraconazole 2-3 times/day 200 mg p.o. or ketoconazole 2-3 times/day 200 mg p.o.

Literature
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  1. Duek L et al (2004) The pathogenesis of dermatophyte infections in human skin sections. J Infect 48: 175-180
  2. Seebacher C (2003) The change of dermatophyte spectrum in dermatomycoses. Mycoses 46 Suppl 1: 42-46

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020