Trichilemmal cyst proliferatingD23.4

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 08.12.2022

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Synonym(s)

Epithelioid cyst proliferating; Giant hair matrix tumor; Giant hair matrix tumor, tricholemic cyst proliferating; Pilar tumor of the scalp; Proliferating trichilemmal cyst; Proliferating trichilemmal tumor; Proliferating tricholemic cyst; Trichilemmal tumor proliferating

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HistoryThis section has been translated automatically.

Wilson-Jones, 1966

DefinitionThis section has been translated automatically.

Usually benign, purely follicularly differentiated adnexal tumor, occurring predominantly on the hairy head, which may assume clinically monstrous dimensions. To what extent there is a nosological relationship to the trichilemmal cyst is unclear. In this respect, some authors prefer the term "proliferating trichilemmal tumor".

ManifestationThis section has been translated automatically.

Mostly occurring in older women (80-90% of cases).

HistologyThis section has been translated automatically.

Multiple cysts of various sizes with mostly pseudoepitheliomatous hyperplasia of the cyst wall, abrupt trichilemmal keratinization; dedifferentiated cell clusters are detectable in some tumors. In isolated cases, lymph node metastases have been detected (Rose C 2014).

TherapyThis section has been translated automatically.

Safe excision in healthy tissue with microscopically controlled surgery.

Progression/forecastThis section has been translated automatically.

Tendency to local recurrence. Infiltrative growth or metastasis are possible.

LiteratureThis section has been translated automatically.

  1. Burg G et al (1988) Proliferating tricholemmal tumor. dermatologist 39: 117-119
  2. Haas N et al (2002) Carcinoma arising in a proliferating trichilemmal cyst expresses fetal and trichilemmal hair phenotype. At J Dermatopathol 24: 340-344
  3. Hödl S et al (1984) On the dignity of the proliferating trichilemmal cyst. Dermatologist 35: 640-644
  4. Noto G et al (1997) Proliferating tricholemmal cyst should always be considered as a low-grade carcinoma. Dermatology 194: 374-375
  5. Rose C (2014) tumors of the scalp. Dermatologist 65: 1030-1036
  6. Van Zele D et al (2002) Invasive tricholemmal carcinoma of the nose. Dermatology 204: 315-317
  7. Jones EW (1966) Proliferating epidermoid cysts. Arch Dermatol 94: 11-19

Authors

Last updated on: 08.12.2022

Author: Prof. Dr. med. Peter Altmeyer