Topoisomerase inhibitors

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Topisomerase inhibitors

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DefinitionThis section has been translated automatically.

Cytostatic drug; inhibitor of the enzyme topoisomerase.

Field of application/useThis section has been translated automatically.

There are 2 types of effect:

  • Inhibitors of topoisomerase I (irinotecan, topotecan) and
  • Inhibitors of topoisomerase II(etoposide, teniposide).

IndicationThis section has been translated automatically.

Dermatological indications exist for etoposide:

LiteratureThis section has been translated automatically.

  1. Lim DS et al (2003) Topoisomerase I inactivation by reticulol and its in vivo cytotoxicity against B16F10 melanoma. Chemotherapy 49: 257-263

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer