DefinitionThis section has been translated automatically.
Virustatic. Inhibitor of HIV protease. Non-peptide protease inhibitor.
Pharmacodynamics (Effect)This section has been translated automatically.
Inhibition of the HIV-1 aspartyl protease and suppression of the maturation of virus particles in the host cell
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IndicationThis section has been translated automatically.
In combination with low-dose ritonavir for antiretroviral combination therapy of HIV-1 infection in multi-treated adult patients with viruses resistant to multiple protease inhibitors.
Dosage and method of useThis section has been translated automatically.
2 times/day 500 mg p.o. each in combination with ritonavir 100 mg p.o.
Undesirable effectsThis section has been translated automatically.
Very often: diarrhoea, nausea. Also: headaches, stomach aches, skin changes. Liver toxicity (increased transaminases).
PreparationsThis section has been translated automatically.
Aptivus
Prof. Dr. med. Peter Altmeyer