DefinitionThis section has been translated automatically.
Tenecteplase belongs to the group of fibrinolytics. It is a recombinant variant or modification of the natural t-PA, which is characterized by three point mutations. Compared to t-PA, the fibrin specificity is 14 times higher. In addition, it has an 80 times higher resistance to the plasminogen activator inhibitor 1.
Dosage and method of useThis section has been translated automatically.
With a body weight between 60-69 kg: 35 mg, with 70-79 kg: 40 mg, with 80-89 kg: 45 mg, > 90 kg:050 mg as an i.v. bolus.
PreparationsThis section has been translated automatically.
Metalysis®
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Scientific Publisher GmbH Berlin
Prof. Dr. med. Peter Altmeyer