Syringofibroadenoma D23.L

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

acrosyringealer; acrosyringeals; Adenomatosis; Adenomatosis acrosyringeale; eccrine; Mascaro tumor; Naevus; Syringofibroadenomatosis; Syringofibroadenomatosis ekkrine

History
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Mascaro, 1963

Definition
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Very rare, benign, eccrine adnexal tumor with acrosyringeal and ductal differentiation.

Localization
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Located on extremities, trunk and face.

Clinical features
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Mostly solitary, skin-coloured or brown, firm knot, with a verrucous or even weeping surface. In rare cases multiple, grouped occurrence.

Histology
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Tumor originating from the surface epithelium and characterized by reticular epithelial branching and a broad, loosened, vascular stroma. The tumor epithelia are small and cuboidal with basophilic nuclei. Differentiation of ductal structures with luminal (CEA-positive) cell layer.

Differential diagnosis
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Therapy
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Excision barely in the healthy area.

Literature
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  1. Bjarke T et al (2003) Carcinoma and eccrine syringofibroadenoma: a report of five cases. J Cutan pathogen 30: 382-392
  2. Endo H et al (2003) Cervical polyp with eccrine syringofibroadenoma-like features. Histopathology 42: 301-304
  3. Ichikawa E et al (2000) Eccrine syringofibroadenoma in a patient with a burn scar ulcer. Br J Dermatol 143: 591-594
  4. Nomura K et al (1991) Eccrine Syringofibroadenomatous hyperplasia in a patient with bullous pemphigoid: a case report and review of the literature. Dermatologica 182: 59-62
  5. Theunis A et al (2001) A case of subungual reactive eccrine syringofibroadenoma. Dermatology 203: 185-187
  6. Viragh P et al (1992) The eccrine syringofibroadenoma. dermatologist 43: 724-727

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020