Sulfadiazine - Altmeyers Encyclopedia - Department Dermatology

Synonym(s)

sulfapyrimidine

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Definition This section has been translated automatically.

Sulfonamide chemotherapy drug.

Half-life This section has been translated automatically.

13–24 h

Indication This section has been translated automatically.

Acute and recurrent toxoplasmosis in combination with pyrimethamine

Dosage and method of use This section has been translated automatically.

Adults: Initially 2-4 g, then every 4-6 hours 1 g p.o.
Children: 65-150 mg/kg bw/day p.o.

Undesirable effects This section has been translated automatically.

Cutaneous ADRs (approx. 10-20% of patients): macular or papular exanthema, angioedema, erythema exsudativum multiforme, photosensitivity.
Also: blood count changes (leukopenia, thrombocytopenia), drug fever, headache and joint pain, gastrointestinal side effects such as nausea, diarrhoea, flatulence, vomiting. Rarely cholestatic hepatosis. Hypoglycemia, kidney or liver damage. Very rarely transitory myopia.

Preparations This section has been translated automatically.

sulfadiazine heyl

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer