Sulfadiazine

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

sulfapyrimidine

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DefinitionThis section has been translated automatically.

Sulfonamide chemotherapy drug.

Half-lifeThis section has been translated automatically.

13–24 h

IndicationThis section has been translated automatically.

Acute and recurrent toxoplasmosis in combination with pyrimethamine

Dosage and method of useThis section has been translated automatically.

  • Adults: Initially 2-4 g, then every 4-6 hours 1 g p.o.
  • Children: 65-150 mg/kg bw/day p.o.

Undesirable effectsThis section has been translated automatically.

  • Cutaneous ADRs (approx. 10-20% of patients): macular or papular exanthema, angioedema, erythema exsudativum multiforme, photosensitivity.
  • Also: blood count changes (leukopenia, thrombocytopenia), drug fever, headache and joint pain, gastrointestinal side effects such as nausea, diarrhoea, flatulence, vomiting. Rarely cholestatic hepatosis. Hypoglycemia, kidney or liver damage. Very rarely transitory myopia.

PreparationsThis section has been translated automatically.

sulfadiazine heyl

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer